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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1952 1
1965 2
1971 1
1973 3
1974 5
1975 4
1976 5
1977 8
1978 6
1979 11
1980 10
1981 8
1982 16
1983 12
1984 17
1985 13
1986 23
1987 26
1988 44
1989 41
1990 63
1991 85
1992 99
1993 101
1994 123
1995 127
1996 130
1997 135
1998 124
1999 122
2000 137
2001 145
2002 153
2003 175
2004 191
2005 241
2006 243
2007 243
2008 325
2009 354
2010 398
2011 402
2012 443
2013 447
2014 515
2015 570
2016 555
2017 595
2018 551
2019 549
2020 552
2021 702
2022 644
2023 570
2024 221

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10,148 results

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Page 1
Cerebrospinal fluid immune dysregulation during healthy brain aging and cognitive impairment.
Piehl N, van Olst L, Ramakrishnan A, Teregulova V, Simonton B, Zhang Z, Tapp E, Channappa D, Oh H, Losada PM, Rutledge J, Trelle AN, Mormino EC, Elahi F, Galasko DR, Henderson VW, Wagner AD, Wyss-Coray T, Gate D. Piehl N, et al. Cell. 2022 Dec 22;185(26):5028-5039.e13. doi: 10.1016/j.cell.2022.11.019. Epub 2022 Dec 13. Cell. 2022. PMID: 36516855 Free PMC article.
In cognitively impaired subjects, downregulation of lipid transport genes in monocytes occurred concomitantly with altered cytokine signaling to CD8 T cells. Clonal CD8 T effector memory cells upregulated C-X-C motif chemokine receptor 6 (CXCR6) in cognitively impai …
In cognitively impaired subjects, downregulation of lipid transport genes in monocytes occurred concomitantly with altered cytokine signalin …
Genetic variants of phospholipase C-gamma2 alter the phenotype and function of microglia and confer differential risk for Alzheimer's disease.
Tsai AP, Dong C, Lin PB, Oblak AL, Viana Di Prisco G, Wang N, Hajicek N, Carr AJ, Lendy EK, Hahn O, Atkins M, Foltz AG, Patel J, Xu G, Moutinho M, Sondek J, Zhang Q, Mesecar AD, Liu Y, Atwood BK, Wyss-Coray T, Nho K, Bissel SJ, Lamb BT, Landreth GE. Tsai AP, et al. Immunity. 2023 Sep 12;56(9):2121-2136.e6. doi: 10.1016/j.immuni.2023.08.008. Epub 2023 Sep 1. Immunity. 2023. PMID: 37659412 Free article.
Genetic association studies have demonstrated the critical involvement of the microglial immune response in Alzheimer's disease (AD) pathogenesis. Phospholipase C-gamma-2 (PLCG2) is selectively expressed by microglia and functions in many immune receptor signaling pathways …
Genetic association studies have demonstrated the critical involvement of the microglial immune response in Alzheimer's disease (AD) pathoge …
CryoEM Status Update and Innovative Developments.
Lytton-Jean AKR, Mankus DV, Bisher ME. Lytton-Jean AKR, et al. J Vis Exp. 2023 Mar 3;(193). doi: 10.3791/65021. J Vis Exp. 2023. PMID: 37602884
Truong, C. D. et al. Sample preparation using a lipid monolayer method for electron crystallographic studies. ...Journal of Visualized Experiments. (184), e64099 (2022). Chang, Y.-C., Chen, C.-Y., Tsai, M.-D. Preparation of high-temperature sample grid …
Truong, C. D. et al. Sample preparation using a lipid monolayer method for electron crystallographic studies. ...Journal of Visualize …
Comment on Tsai, Y.-C., et al. Association of Stress-Induced Hyperglycemia and Diabetic Hyperglycemia with Mortality in Patients with Traumatic Brain Injury: Analysis of a Propensity Score-Matched Population. Int. J. Environ. Res. Public Health 2020, 17, 4266.
Mekitarian Filho E. Mekitarian Filho E. Int J Environ Res Public Health. 2021 Mar 4;18(5):2533. doi: 10.3390/ijerph18052533. Int J Environ Res Public Health. 2021. PMID: 33806338 Free PMC article.
I read carefully the great study published by Tsai, Y [...]....
I read carefully the great study published by Tsai, Y [...]....
Reply to Comment on Tsai, Y.-C., et al. Association of Stress-Induced Hyperglycemia and Diabetic Hyperglycemia with Mortality in Patients with Traumatic Brain Injury: Analysis of a Propensity Score-Matched Population. Int. J. Environ. Res. Public Health 2020, 17, 4266.
Tsai YC, Wu SC, Hsieh TM, Liu HT, Huang CY, Chou SE, Su WT, Hsu SY, Hsieh CH. Tsai YC, et al. Int J Environ Res Public Health. 2021 Mar 4;18(5):2531. doi: 10.3390/ijerph18052531. Int J Environ Res Public Health. 2021. PMID: 33806330 Free PMC article.
HLA-Cw1 and Psoriasis.
Huang YW, Tsai TF. Huang YW, et al. Am J Clin Dermatol. 2021 May;22(3):339-347. doi: 10.1007/s40257-020-00585-1. Epub 2021 Jan 18. Am J Clin Dermatol. 2021. PMID: 33460021 Free PMC article. Review.
For example, cytotoxic T lymphocytes recognize multiple cytomegalovirus pp65-derived epitopes presented by HLA alleles, including HLA-C*01:02. In addition, cytomegalovirus can lead to severe exacerbation of psoriatic skin disease. ...
For example, cytotoxic T lymphocytes recognize multiple cytomegalovirus pp65-derived epitopes presented by HLA alleles, including HLA-C …
Syndemic theory, methods, and data.
Mendenhall E, Newfield T, Tsai AC. Mendenhall E, et al. Soc Sci Med. 2022 Feb;295:114656. doi: 10.1016/j.socscimed.2021.114656. Epub 2021 Dec 14. Soc Sci Med. 2022. PMID: 34949486 Free PMC article. No abstract available.
IgG4-related myositis.
Tsai MK, Kuo CW, Chang LC. Tsai MK, et al. QJM. 2019 Nov 1;112(11):872-873. doi: 10.1093/qjmed/hcz195. QJM. 2019. PMID: 31393592 No abstract available.
Plaque attack by microglial PLCγ2.
Comer AL, Hammond TR. Comer AL, et al. Immunity. 2023 Sep 12;56(9):1985-1987. doi: 10.1016/j.immuni.2023.08.012. Immunity. 2023. PMID: 37703828
PLCgamma2 is genetically linked to Alzheimer's disease (AD), but it is unclear how PLCgamma2 contributes to pathology. Tsai et al. demonstrate that AD-associated PLCG2 variants bidirectionally orchestrate microglial responses to plaques and impact neural function in an AD …
PLCgamma2 is genetically linked to Alzheimer's disease (AD), but it is unclear how PLCgamma2 contributes to pathology. Tsai et al. de …
Akt: a key transducer in cancer.
Tsai PJ, Lai YH, Manne RK, Tsai YS, Sarbassov D, Lin HK. Tsai PJ, et al. J Biomed Sci. 2022 Oct 1;29(1):76. doi: 10.1186/s12929-022-00860-9. J Biomed Sci. 2022. PMID: 36180910 Free PMC article. Review.
10,148 results
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